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GLP-1-RA reduzieren in der Therapie des T2D auch das Krpergewicht GLP-1 und GLP-1-RA, wie zur Therapie des T2D zugelassen, spielen eine Rolle in der Regulation von Appetit, Sttigung und der gefhlten Bereitschaft zu essen (45, 46)
In addition, FIN56 is capable of binding and activating squalene synthase, and leads to depleting coenzyme Q10 (CoQ10) (Shimada et al., 2016), which is a vital antioxidant by directly reducing lipid peroxyl radicals (Ernster and Forsmark-Andree,1993)
Paired-end sequencing of the library was performed using the Illumina HiSeq platform (Illumina Inc., San Diego, CA, USA)
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